Application

(±)-Mevalonolactone is used to:study the effect of statin on the prenylation of Ras and Rho GTPasesanalyse the isoprenoid biosynthesis pathways in Listeria monocytogenesstudy the the effects of statins on proliferation and migration of HUVECs (HGF-induced human umbilical vein endothelial cells)

General description

Alkaline hydrolysis of mevalonolactone gives mevalonate. Mevalonate is a precursor of farnesyl and geranylgeranyl pyrophosphates. These pyrophosphates are required for protein prenylation.

Other Notes

May also be liquid!

Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. M4667.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.

Packaging

1, 5, 10 g in glass bottle